Attenuated vaccine against cholera (CV638)

Clinical trials.

The National Center for Scientific Research and the Finlay Institute of Vaccines are working on the development of an attenuated vaccine based on the genetically modified strain of Vibrio cholerae 638 (O1, El Tor biotype, Ogawa serotype). The administration of a single dose of this vaccine candidate has demonstrated a high colonizing capacity, as well as the induction of a high and protective vibriocidal immune response in clinical studies.